Edibles

 

Why do we ask you for information about your edible products ?

We request that each customer fills out an informational form when they turn in any sample that is to be tested on our HPLC machine as an infused product or an edible concentrate (RSO). This information helps us determine the correct method to prepare and test your sample, reducing the risk of damaging any part of our expensive machinery as well as preventing the need for supplemental expensive testing, which may come at an additional cost to the customer. That being said, not every field needs to be filled out for every sample, and some fields are optional and used only for diagnosing and solving problems for the client.

The two most important fields to fill out are the ‘Serving Size’ and the ‘Method of Mixing’ fields. Serving size describes the amount of product that contains one full “dose” of medicine. This information is different for every sample and is very valuable for the patient. The method of mixing tells us if you have a homogenous or non-homogenous product and which portion of the product may be medicated, and allows us to determine a proper method of preparing and testing your sample.

Information such as estimated strength of product or amount of cannabis added to the product helps us determine the appropriate concentration to prepare your sample at (i.e. not too strong or weak), which again prevents additional expensive testing. Telling us the ingredients used indicates whether special measures must be taken to prevent the sample from clogging or otherwise damaging our machine. The time and temperature fields do not need to be filled out but are useful if you would like to discuss the results of your tests with the technician, and may be useful for us helping you to improve your product in the future. Finally the additional notes field can be used for anything you may want to tell your edible technician so we may be of the best service to you.

The serving size field may be filled out by the customer or it will be assigned a default value based on the type of product it is. Ideally, we ask that you weigh one dose of infused product (in grams), not including the weight of any capsule, syringe, muffin tin, or other container that may be on your product. The most accurate way to determine a serving size would be to separately measure the weight of several doses and take the average value for you data. This would give the most accurate value for your batch as a whole. If this weight is not known or cannot be determined by the customer, it may be left blank and will be assigned a default serving size based on the type of product it is.

Table of Default Serving Sizes:

*If samples are very non-viscous (very liquidy/not thick), then the serving size may be designated as a volume with either units of milliliters or US fluid ounces. In this scenario we would measure the density of your product and use it to calculate the weight of the indicated serving size volume provided.

**Please indicate if your edible concentrate/RSO has been diluted at all and to what extent. This affects the method of preparation of your sample.

 What does activation mean?

 Please click on the link below for a brief explanation on THCA, THC, activation, and decarboxylation.

 THC, THCA, and THC Activation.pdf

 

 How do I interpret my edible test results?

 

  1. This row of values represents the concentration of each tested cannabinoid in mg/g (milligrams of cannabinoid per gram of sample).
  • CBDA = Cannabidiolic acid. This is the “un-activated” form of CBD.
  • CBD = Cannabidiol. This cannabinoid modulates the effects of THC.
  • CBN = Cannabinol.  This cannabinoid is a degradation product of THC and other cannabinoids.
  • ∆9 THC = Tetrahydrocannabinol.  This is the “activated” psychoactive form of THC.
  • THCA = Tetrahydrocannabinolic acid.  This is the “un-activated” non-psychoactive form of THC.
  1. The THC activation percentage is the result of a mathematical calculation to determine what percentage of the combined THCA & THC molecules are in the activated THC form.  To do this, we use the following equation (Eq.1):

                       

*The CBD activation percentage is calculated in the same fashion as THC (i.e. substituting CBD for THC & CBDA for THCA in the equation).

  1. The serving size is determined by what is entered on the “Data Sheet for Infused & Edible Sample” document.  If there is no accompanying information provided, we will weigh the sample submitted and use that value as the serving size.  RSO, vape fluids, some glycerites, and unknown liquid samples are generally assigned a sample size of 1 g.  Butter and oil samples are generally assigned a sample size of 14 g (the approximate mass of a tablespoon of water).
  1. Amount of cannabinoids per serving.  To calculate these values, we multiply the serving size (g/serving) with the corresponding cannabinoid concentration (in mg/g), to get mg/serving for that particular cannabinoid.
  1. Total Cannabinoids.  This column reports the total cannabinoid concentration both in mg/g and mg/serving.  Total cannabinoid concentration is determined by adding the values of each compound tested (i.e. (CBDA + CBD + CBN + ∆9 THC + THCA).

References:

McPartland, J. M., & Russo, E. B. (2001). Cannabis and cannabis extracts: greater than the sum of their parts? Journal of Cannabis Therapeutics, 1(3-4), 103–132.

 

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